Low concentrations of Lactobacillus rhamnosus GG ( Yoba®) are safe in male Drosophila melanogaster
Loading...
Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
BMC Res Notes
Abstract
Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives
were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118
Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan.
Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total
protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba
® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster.
Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study.
Description
Keywords
Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, Aging
Citation
Kasozi et al