Browsing by Author "Kellinga Alexandra"

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    A Revised Protecting Group Strategy Enables a Divergent Synthesis of Prenylated Isoflavones from Psoralea corylifolia
    (Synthesis, 2025) Gliszczinskia Sarah von Chamier; Sperlicha Eric; Kellinga Alexandra; Kwesiga George; Schmidt Bernd
    Three bioactive prenylated isoflavone natural products were synthesized for the first time, using a combination of Pd-catalyzed Suzuki–Miyaura coupling for installing the B-ring, microwave-promoted Claisen rearrangement of allyl ethers, and Ru-catalyzed olefin cross me tathesis for obtaining the prenyl substituents. Careful consideration of the protecting group strategy turned out to be vital for the success of these total syntheses.