Browsing School of Medicine (KABSOM) by Title
Now showing items 1-20 of 110
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African animal trypanocide resistance: A systematic review and meta-analysis
(frontiersin.org, 2023)Background: African animal trypanocide resistance (AATr) continues to undermine global efforts to eliminate the transmission of African trypanosomiasis in endemic communities. The continued lack of new trypanocides has ... -
Allium Cepa (Onion) Extract Enhances and Protects Testicular Function and Architecture against Paraquat Induced Oxidative Damage.
(International Journal of Life science and Pharma Research, 2020)Allium cepa (A. cepa) is consumed for its health benefits. This study investigated the therapeutic potentials of ethanolic extract of A. cepa bulbs against paraquat-induced testicular toxicity in animal model. Thirty Wistar ... -
Amaranth leaf extract protects against hydrogen peroxide induced oxidative stress in Drosophila melanogaster
(BMC, 2021)Objective: Amaranths leaves are rich in ascorbic acid and polyphenol compounds which have antioxidant activity. The aim of this study was to evaluate their in vivo antioxidant activity. The effect of consumption of Amaranth ... -
Analgesic Appraisal of Bidens pilosa (Asteraceae) Leaf Extracts Used in Management of Oral Lesion Pain in HIV/AIDS Patients in Rodents
(Scientific Research Publishing Inc., 2018-06-29)Oral lesions, diarrhoea, Pneumocystis carinii pneumonia, tuberculosis and urinary tract infections are some of the opportunistic infections (OIs) which arise when the CD4 cells of the HIV/AIDS patient fall below 200 ... -
An analysis of heavy metals contamination and estimating the daily intakes of vegetables from Uganda
(Toxicology Research and Application, 2021)Environmental contamination with elevated levels of copper (Cu), cobalt (Co), iron (Fe), zinc (Zn), lead (Pb), chromium (Cr6þ), cadmium (Cd), and nickel (Ni)—all states of which are found in Uganda—raises health risk to ... -
An analysis of heavy metals contamination and estimating the daily intakes of vegetables from Uganda
(Toxicology Research and Application, 2021)Environmental contamination with elevated levels of copper (Cu), cobalt (Co), iron (Fe), zinc (Zn), lead (Pb), chromium (Cr 6þ), cadmium (Cd), and nickel (Ni)—all states of which are found in Uganda—raises health risk to ... -
Annona muricata Linn and Khaya grandifoliola C.DC. Reduce Oxidative Stress In Vitro and Ameliorate Plasmodium berghei-Induced Parasitemia and Cytokines in BALB/c Mice
(Journal of Evidence-Based Integrative Medicine, 2021)Background. Annona muricata and Khaya grandifoliola are ethnomedicinally used for the treatment of malaria and have been experimentally shown to have an anti-plasmodial effect, but the mechanisms involved are not fully ... -
Anti-Malarial Effects of Five Traditional Nigerian Medicinal Plant Extracts on Plasmodium Berghei-Infected Rats
(FUDMA Journal of Sciences (FJS), 2021)This work focusses on comparative determination of the effects of plant extracts: bitter leaf (BL), sour lime (SL), grape (G), pawpaw (PP) and unripe pineapple (UPA) in female rats induced into malaria with Plasmodiumberghei. ... -
Anti-obesity effects of Erythrina abyssinica stem bark extract in flies exposed to a high fat diet
(www.cell.com/heliyon, 2022-08)Background: An in vitro assay on Sigmoidin A from Erythrina abyssinica stem bark revealed its potency to inhibit pancreatic lipase. However, studies indicate activity of extract bioactive compounds in combination far ... -
Antimalarial Combination Therapies Increase Gastric Ulcers Through an Imbalance of Basic Antioxidative‑Oxidative Enzymes in Male Wistar Rats.
(Kabale University, 2020)Objective: Antimalarials are globally used against plasmodium infections, however, information on the safety of new antimalarial combination therapies on the gastric mucosa is scarce. The aim of this study was to investigate ... -
Antimicrobial resistance profile among bacteria isolated from patients presenting with wounds at Kabale Regional Referral Hospital, South western Uganda
(Research Square, 2020)Background: Bacterial Wound infection and antimicrobial resistance remains a public health challenge. The challenge remains worse due to nosocomial bacterial infection often characterized by multidrug resistance. Infected ... -
Anxiety, Anger and Depression Amongst Low-Income Earners in Southwestern Uganda During the COVID-19 Total Lockdown
(Kabale University, 2021)Background: Low-income earners are particularly vulnerable to mental health, consequence of the coronavirus disease 2019 (COVID-19) lockdown restrictions, due to a temporary or permanent loss of income and livelihood, ... -
Assessing Knowledge, Attitudes and Practice of Hand Washing with Soap among Mothers and Caregivers of Children under Five years in Ntungamo District, Uganda
(Texila International Journal of Public Health, 2020)Background: The study of hand washing practices in Ntungamo district is part of a larger strategy being implemented in different countries to decrease the prevalence of childhood diarrhea, in the frame work of the global ... -
Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections
(Frontiers in Public Health, 2020)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by severe cytokine storm syndrome following inflammation. SARS-CoV-2 directly interacts with angiotensin-converting enzyme 2 (ACE-2) receptors ... -
Behavioural Response To Self-Medication Practice Before and During Covid-19 Pandemic in Western Uganda
(Patient Preference and Adherence, 2022)Background: Self-medication has become a serious public health problem posing great risks, especially with the increasing number of cases of COVID-19 disease globally and in Uganda. This may be partly because of the absence ... -
Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids
(International Journal of Molecular Science, 2020-07-22)Pepper originated from the Capsicum genus, which is recognized as one of the most predominant and globally distributed genera of the Solanaceae family. It is a diverse genus, consisting of more than 31 different species ... -
Birthing experience and quality of life after vacuum delivery and second-stage caesarean section: a prospective cohort study in Uganda
(Tropical Medicine and International Health, 2018)objective To assess perceptions of women undergoing vacuum extraction or second-stage caesarean section (SSCS) in a tertiary referral hospital in sub-Saharan Africa. methods Prospective cohort study, with six-month ... -
Borassus aethiopum (Mart.) ethanol fruit extract reverses alloxan-treatment alterations in experimental animals
(Mediterranean Journal of Nutrition and Metabolism 15 (2022) 429–44, 2022)BACKGROUND: Borassus aethiopum fruit is claimed to be used for the management of diabetes without scientific validation. OBJECTIVE: This study seeks to evaluate the antihyperglycaemic activity of ethanol fruit extract of ... -
Calcium and s100a1 Protein Balance in the brain– Heart axis in Diabetic Male Wistar Rats.
(Kabale University, 2021)Objectives: Calcium deregulation in diabetes mellitus (DM) is central to the brain–heart axis pathology. This has led to the use of medical plants in complementary medicine such as Amaranthus hypochondriacus (GA). The ... -
Calcium and s100a1 Protein Balance in the brain– Heart axis in Diabetic Male Wistar Rats.
(2020)Calcium deregulation in diabetes mellitus (DM) is central to the brain–heart axis pathology. This has led to the use of medical plants in complementary medicine such as Amaranthus hypochondriacus (GA). The objective of ...
