Keneth Iceland, KasoziAisha, BukenyaEjike, Daniel EzeJosephine, KasoloDickson Stuart, TayebwaFred, SsempijjaJoy, SuuboAndrew, TamaleIsaac, EchoruIbrahim, NtulumeSarah, Kemuma OnkobaLisa Nkatha, MicheniEmmanuel Tiyo, AyikobuaOscar Hilary, AsiimweMuhamudu, Kalange2019-06-142019-06-142019Kasozi et alhttp://hdl.handle.net/20.500.12493/170Objective: The purpose of the study was to generate information on the safety of probiotics, thus the study objectives were to evaluate the effects of Yoba ® on basic physiochemical properties. The study assessed male w1118 Drosophila melanogaster which were provided food supplemented with Yoba ® at 1%, 3%, 6%, and 12% on motor function, total protein, catalase activity, and hydrogen peroxide scavenging activity and lifespan. Results: Yoba® at high concentration (≥ 6%) increased locomotor activity in Drosophila melanogaster, however, total protein, catalase, and hydrogen peroxide scavenging activity were significantly higher at 1% Yoba ® compared to 3%, 6%, and 12% Yoba ®. Yoba consumed at 1% was associated with greater physiological benefits in Drosophila melanogaster. Findings in the study offer a rationale for the consumption of Yoba ® at 1% in humans as is currently being promoted by the Yoba for Life consortium, however, high concentrations of Yoba ® would disrupt physiological function as shown by this study.Probiotics, Yoba for life, Nutritional toxicology, Yoghurt, Food supplements, Catalase, Hydrogen peroxide scavenging, AgingArticle