Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension.

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dc.contributor.authorKazibwe, Richard
dc.contributor.authorSchaich, Christopher L.
dc.contributor.authorMuhammad, Ahmad Imtiaz
dc.contributor.authorEpiu, Isabella
dc.contributor.authorNamutebi, Juliana H.
dc.contributor.authorChevli, Parag A.
dc.contributor.authorKazibwe, Joseph
dc.contributor.authorHughes, Timothy
dc.contributor.authorRikhi, Rishi R.
dc.contributor.authorShapiro, Michael D.
dc.contributor.authorYeboah, Joseph
dc.date.accessioned2024-06-07T15:26:15Z
dc.date.available2024-06-07T15:26:15Z
dc.date.issued2024
dc.description.abstractIntroduction: We investigated the effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension. Methods: Baseline self-reported frequency of VPA was categorized into low VPA (<1 session/week), and high VPA (≥1 session/week). We used multivariate Cox regression analysis to examine the association of VPA categories with incident MCI and probable dementia events. Results: Participants in the high VPA category, compared with low VPA, experienced lower events rates (per 1000 person-years) of MCI (13.9 vs 19.7), probable dementia (6.3 vs 9.0), and MCI/probable dementia (18.5 vs 25.8). In the multivariate Cox regression model, high VPA, compared with low VPA, was associated with lower risk of MCI, probable dementia, and MCI/probable dementia (HR [95% CI]: 0.81 [0.68–0.97], 0.80 [0.63–1.03], and 0.82 [0.70–0.96]), respectively. DISCUSSION: This study provides evidence that VPA may preserve cognitive function in high-risk patients with hypertension.
dc.identifier.citationKazibwe, Richard et al. (2024). Effect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension. Kabale: Kabale University.
dc.identifier.urihttp://hdl.handle.net/20.500.12493/2059
dc.language.isoen_US
dc.publisherKabale University
dc.subjectCognitive Impairment
dc.subjectDementia
dc.subjectHypertension
dc.subjectMild Cognitive Impairment
dc.subjectPhysical Activity
dc.titleEffect of Vigorous-Intensity Physical Activity on Incident Cognitive Impairment in High-Risk Hypertension.
dc.typeArticle

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