Lycopene improves on basic hematological and immunological parameters in diabetes mellitus
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
BMC Research Notes
Abstract
Objective: Diabetes is associated with an upset of hematological and immunological parameters in humans, how-
ever information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes
in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been
reported.
Results: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these obser-
vations were dose independent. There was a decrease in neutrophil, low neutrophil–lymphocyte ratio and platelet
counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic
hematological physiological variables.
Description
Keywords
Antioxidants, Diabetes, Anemia, Carotenoids, Blood