Browsing by Author "Archibong, Victor Bassey"

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    Community Drivers Affecting Adherence to WHO Guidelines Against COVID-19 Amongst Rural Ugandan Market Vendors.
    (Kabale University, 2020) Usman, Ibe Michael; Ssempijja, Fred; Ssebuufu, Robinson; Lemuel, Ann Monima; Archibong, Victor Bassey; Ayikobua, Emmanuel Tiyo; Aruwa, Joshua Ojodale; Kembabazi, Stellamaris; Kegoye, Eric Simidi; Ayuba, John Tabakwot; Okeniran, Olatayo Segun; Echoru, Isaac; Adeoye, Azeez; Mujinya, Regan; Nankya, Viola; Keneth Iceland, Kasozi,
    Background: Market vendors occupy a strategic position in the fight against the spread of SARS CoV-2 in rural Uganda. To successfully contain the spread of the virus, special attention needs to be given to this set of people by assessing the type of information, source of information, and practices they inculcate as regards adherence to WHO guidelines in the fight against COVID-19 in Uganda. The study aimed to assess the role of information sources, education level, and phone internet connectivity in influencing COVID-19 knowledge among the rural market vendors; and the relationship existing between knowledge, attitude, and practices among them. Methods: The study was a descriptive cross-sectional study among rural market vendors (n = 248) in southwestern Uganda. Information was collected using a questionnaire and descriptively presented as frequency and percentages. Results: The study showed that the majority of the rural market vendors had sufficient information regarding COVID-19 with the majority being female individuals and have attained a secondary level of education, The general percentage score for knowledge, attitude, and practices were (75.57, 82.6, and 76.50% respectively). There was a positive correlation between attitude and practices (r = 0.17, p = 0.007), as well as their knowledge with practices (r = 0.29, p < 0.001). The majority of the people in the population did not have their phones connected to the internet (OR = 1.96, 95%CI: 1.16–3.31, P = 0.01). The majority of people received their information regarding COVID-19 from one source (radio) (OR = 1.55). Conclusion: Where and how the rural market vendors get their information and education level are vital in breaking COVID 19 infection circle in line with WHO guidelines. Therefore, sources of information and education level played a key role in molding their knowledge and practices. However, the level of knowledge on COVID 19 among our respondents was not linked with phone internet connectivity. Keywords: COVID-19, SARS CoV-2, market-vendors, Information, Rural Community, Africa Response, Uganda
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    Tamarindus Indica Ameliorates Behavioral and Cytoarchitectural Changes in the Cerebellar Cortex Following Prenatal Aluminum Chloride Exposure in Wistar Rats.
    (Kabale University, 2022) Usman, Ibe Michael; Adebisi, Samuel Sunday; Musa, Sunday Abraham; Iliya, Ibrahim Abdullahi; Archibong, Victor Bassey; Lemuel, Ann Monima; Keneth Iceland, Kasozi
    Aluminium exposure has been linked with developmental neurotoxicity in humans and experimental animals.The study aimed to evaluate the ameliorative effect of Tamarindus indica on the developing cerebellar cortex, neurobehavior, and immunohistochemistry of the cerebellar cortex following prenatal aluminum chloride (AlCl3) exposure. Pregnant timed Wistar rats were divided into 5 groups (n=4). Group I (negative control) was given distilled water, group II was treated with 200 mg/kg of AlCl3, group III were given 200 mg/kg of AlCl3 and 400 mg/kg of ethyl acetate leaf fraction of Tamarindus indica (EATI), group IV were given 200 mg/kg of AlCl3 and 800 mg/kg of EATI, and group V were treated with 200 mg/kg of AlCl3 s/c and 300 mg/kg of vitamin E for 14 days (prenatal day 7–21) via the oral route. Male pups (n=6) were randomly selected and taken for neurobehavioral studies, and humanely sacrificed via intraperitoneal injection of thiopental sodium. The cerebellum was removed, fixed and tissue processed for histological and immunohistochemical studies. The results revealed that prenatal AlCl3 exposure impacted neurodevelopment and neurobehaviour among exposed pups. Prenatal AlCl3 exposure was marked with delayed cytoarchitectural development of the cerebellar cortex and increased GFAP expression inthe cerebellar cortex. On the other hand, treatment with EATI and vitamin E were marked with significant improvements.The present study therefore concluded treatment with EATI shows an ameliorative effect to prenatal AlCl3 exposure. Key words: Tamarindus Indica, Glial Fibrillary Protein, Motor Cordination, Aluminum Exposure